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GABAρ1/GABA(A)α1 receptor chimeras to study receptor desensitization

γ-Aminobutyrate type C (GABA(C)) receptors are ligand-gated ion channels that are expressed preponderantly in the vertebrate retina and are characterized, among other things, by a very low rate of desensitization and resistance to the specific GABA(A) antagonist bicuculline. To examine which structu...

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Bibliographic Details
Main Authors: Martínez-Torres, Ataúlfo, Demuro, Angelo, Miledi, Ricardo
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC16279/
https://ncbi.nlm.nih.gov/pubmed/10725369
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