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Neurosteroid Prolongs GABA(A) Channel Deactivation by Altering Kinetics of Desensitized States

Fast applications of GABA (1 mm) to nucleated and outside-out patches excised from granule neurons in cerebellar slices from developing rats evoked currents with a double exponential time course reminiscent of that of IPSCs. A neurosteroid 3α, 21dihydroxy-5α-pregnan-20-one (THDOC) remarkably increas...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhu, Wei Jian, Vicini, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573570/
https://ncbi.nlm.nih.gov/pubmed/9151718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-11-04022.1997
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