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Chlorpromazine Inhibits Miniature GABAergic Currents by Reducing the Binding and by Increasing the Unbinding Rate of GABA(A)Receptors

Recent studies have emphasized that nonequilibrium conditions of postsynaptic GABA(A) receptor (GABA(A)R) activation is a key factor in shaping the time course of IPSCs (Puia et al., 1994; Jones and Westbrook, 1995). Such nonequilibrium, resulting from extremely fast agonist time course, may affect...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Mozrzymas, Jerzy W., Barberis, Andrea, Michalak, Krystyna, Cherubini, Enrico
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786064/
https://ncbi.nlm.nih.gov/pubmed/10087062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-07-02474.1999
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