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Zinc Inhibits Miniature GABAergic Currents by Allosteric Modulation of GABA(A) Receptor Gating

Zinc is abundantly present in the CNS, and after nerve stimulation is thought to be released in sufficient quantity to modulate the synaptic transmission. Although it is known that this divalent cation inhibits the GABAergic synaptic currents, the underlying mechanisms were not fully elucidated. Her...

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Vydáno v:J Neurosci
Hlavní autoři: Barberis, Andrea, Cherubini, Enrico, Mozrzymas, Jerzy W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773059/
https://ncbi.nlm.nih.gov/pubmed/11102466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-23-08618.2000
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