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Pten loss results in inappropriate excitatory connectivity

Pten mutations are associated with Autism Spectrum Disorder. Pten loss of function in neurons increases excitatory synaptic connectivity, contributing to an imbalance between excitation and inhibition. We aimed to determine whether Pten loss results in aberrant connectivity in neural circuits. We co...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Skelton, Patrick D., Frazel, Paul W., Lee, Daehoon, Suh, Hoonkyo, Luikart, Bryan W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785382/
https://ncbi.nlm.nih.gov/pubmed/30967683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0412-6
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