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The Role of PTEN in Neurodevelopment
PTEN is a lipid and protein phosphatase that regulates cell growth and survival. Mutations to PTEN are highly penetrant for autism spectrum disorder (ASD). Here, we briefly review the evidence linking PTEN mutations to ASD and the mouse models that have been used to study the role of PTEN in neurode...
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| Vydáno v: | Mol Neuropsychiatry |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
S. Karger AG
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7206585/ https://ncbi.nlm.nih.gov/pubmed/32399470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000504782 |
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