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Rational Design of an Orthogonal Pair of Bimolecular RNase P Ribozymes through Heterologous Assembly of Their Modular Domains

The modular structural domains of multidomain RNA enzymes can often be dissected into separate domain RNAs and their noncovalent assembly can often reconstitute active enzymes. These properties are important to understand their basic characteristics and are useful for their application to RNA-based...

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Dettagli Bibliografici
Pubblicato in:Biology (Basel)
Autori principali: Nozawa, Yuri, Hagihara, Megumi, Rahman, Md Sohanur, Matsumura, Shigeyoshi, Ikawa, Yoshiya
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783828/
https://ncbi.nlm.nih.gov/pubmed/31480450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology8030065
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