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Rational Design of an Orthogonal Pair of Bimolecular RNase P Ribozymes through Heterologous Assembly of Their Modular Domains

The modular structural domains of multidomain RNA enzymes can often be dissected into separate domain RNAs and their noncovalent assembly can often reconstitute active enzymes. These properties are important to understand their basic characteristics and are useful for their application to RNA-based...

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Bibliografiske detaljer
Udgivet i:Biology (Basel)
Main Authors: Nozawa, Yuri, Hagihara, Megumi, Rahman, Md Sohanur, Matsumura, Shigeyoshi, Ikawa, Yoshiya
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783828/
https://ncbi.nlm.nih.gov/pubmed/31480450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology8030065
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