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Rational Design of an Orthogonal Pair of Bimolecular RNase P Ribozymes through Heterologous Assembly of Their Modular Domains

The modular structural domains of multidomain RNA enzymes can often be dissected into separate domain RNAs and their noncovalent assembly can often reconstitute active enzymes. These properties are important to understand their basic characteristics and are useful for their application to RNA-based...

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書目詳細資料
發表在:Biology (Basel)
Main Authors: Nozawa, Yuri, Hagihara, Megumi, Rahman, Md Sohanur, Matsumura, Shigeyoshi, Ikawa, Yoshiya
格式: Artigo
語言:Inglês
出版: MDPI 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783828/
https://ncbi.nlm.nih.gov/pubmed/31480450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology8030065
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