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Rational optimization of the DSL ligase ribozyme with GNRA/receptor interacting modules

The DSL ribozyme is a class of artificial ligase ribozymes with a highly modular architecture, which catalyzes template-directed RNA ligation on a helical substrate module that can be either covalently connected (cis-DSL) or physically separated (trans-DSL) from the catalytic module. Substrate recog...

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Bibliografske podrobnosti
Main Authors: Ishikawa, Junya, Matsumura, Shigeyoshi, Jaeger, Luc, Inoue, Tan, Furuta, Hiroyuki, Ikawa, Yoshiya
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826975/
https://ncbi.nlm.nih.gov/pubmed/19728985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.08.020
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