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Rational optimization of the DSL ligase ribozyme with GNRA/receptor interacting modules
The DSL ribozyme is a class of artificial ligase ribozymes with a highly modular architecture, which catalyzes template-directed RNA ligation on a helical substrate module that can be either covalently connected (cis-DSL) or physically separated (trans-DSL) from the catalytic module. Substrate recog...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826975/ https://ncbi.nlm.nih.gov/pubmed/19728985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.08.020 |
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