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Artificial RNA Motifs Expand the Programmable Assembly between RNA Modules of a Bimolecular Ribozyme Leading to Application to RNA Nanostructure Design

A bimolecular ribozyme consisting of a core ribozyme (ΔP5 RNA) and an activator module (P5abc RNA) has been used as a platform to design assembled RNA nanostructures. The tight and specific assembly between the P5abc and ΔP5 modules depends on two sets of intermodule interactions. The interface betw...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biology (Basel)
Hauptverfasser: Rahman, Md. Motiar, Matsumura, Shigeyoshi, Ikawa, Yoshiya
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745442/
https://ncbi.nlm.nih.gov/pubmed/29084145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology6040037
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