Dimethylaminomicheliolide (DMAMCL) Suppresses the Proliferation of Glioblastoma Cells via Targeting Pyruvate Kinase 2 (PKM2) and Rewiring Aerobic Glycolysis

Glioblastoma (GBM) is the most prevalent malignant tumor in the central nervous system. Aerobic glycolysis, featured with elevated glucose consumption and lactate production, confers selective advantages on GBM by utilizing nutrients to support rapid cell proliferation and tumor growth. Pyruvate kin...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Oncol
Egile Nagusiak: Guo, Jianshuang, Xue, Qingqing, Liu, Kaihui, Ge, Weizhi, Liu, Wenjie, Wang, Jiyan, Zhang, Mengyi, Li, Qiu-ying, Cai, Dongpo, Shan, Changliang, Zhang, Chunze, Liu, Xinqi, Li, Jing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Oncology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783512/
https://ncbi.nlm.nih.gov/pubmed/31632919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00993
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