No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

The Warburg effect describes the circumstance that tumor cells preferentially use glycolysis rather than oxidative phosphorylation for energy production. It has been reported that this metabolic reconfiguration originates from a switch in the expression of alternative splice forms (PKM1 and PKM2) of...

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Autors principals: Bluemlein, Katharina, Grüning, Nana-Maria, Feichtinger, René G., Lehrach, Hans, Kofler, Barbara, Ralser, Markus
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2011
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248187/
https://ncbi.nlm.nih.gov/pubmed/21789790
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