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Pyruvate Kinase M2 and Cancer: The Role of PKM2 in Promoting Tumorigenesis
Pyruvate kinase plays a pivotal role in regulating cell metabolism. The final and rate-limiting step of glycolysis is the conversion of Phosphoenolpyruvate (PEP) to Pyruvate, which is catalyzed by Pyruvate Kinase. There are four isomeric, tissue-specific forms of Pyruvate Kinase found in mammals: PK...
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| Publicado no: | Front Oncol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7061896/ https://ncbi.nlm.nih.gov/pubmed/32195169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00159 |
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