Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis

The glycolytic enzyme pyruvate kinase (PK) is required for cancer development, and has been implicated in the metabolic transition from oxidative to fermentative metabolism, the Warburg effect. However, the global metabolic response that follows changes in PK activity is not yet fully understood. Us...

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Detalhes bibliográficos
Main Authors: Bluemlein, Katharina, Glückmann, Matthias, Grüning, Nana-Maria, Feichtinger, René, Krüger, Antje, Wamelink, Mirjam, Lehrach, Hans, Tate, Stephen, Neureiter, Daniel, Kofler, Barbara, Ralser, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717798/
https://ncbi.nlm.nih.gov/pubmed/23154538
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