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No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

The Warburg effect describes the circumstance that tumor cells preferentially use glycolysis rather than oxidative phosphorylation for energy production. It has been reported that this metabolic reconfiguration originates from a switch in the expression of alternative splice forms (PKM1 and PKM2) of...

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Main Authors: Bluemlein, Katharina, Grüning, Nana-Maria, Feichtinger, René G., Lehrach, Hans, Kofler, Barbara, Ralser, Markus
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248187/
https://ncbi.nlm.nih.gov/pubmed/21789790
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