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PKM2 and cancer: The function of PKM2 beyond glycolysis

Metabolic reprogramming is a hallmark of cancer cells and is used by cancer cells for growth and survival. Pyruvate kinase muscle isozyme M2 (PKM2) is a limiting glycolytic enzyme that catalyzes the final step in glycolysis, which is key in tumor metabolism and growth. The present review discusses t...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: DONG, GAOCHAO, MAO, QIXING, XIA, WENJIE, XU, YOUTAO, WANG, JIE, XU, LIN, JIANG, FENG
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774429/
https://ncbi.nlm.nih.gov/pubmed/26998110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4168
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