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Abnormalities in proinsulin processing in islets from individuals with longstanding T1D

We recently described the persistence of detectable serum proinsulin in a large majority of individuals with longstanding type 1 diabetes (T1D), including individuals with undetectable serum C-peptide. Here, we sought to further explore the mechanistic etiologies of persistent proinsulin secretion i...

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Xehetasun bibliografikoak
Argitaratua izan da:Transl Res
Egile Nagusiak: SIMS, EMILY K., SYED, FAROOQ, NYALWIDHE, JULIUS, BAHNSON, HENRY T., HAATAJA, LEENA, SPEAKE, CATE, MORRIS, MARGARET A., BALAMURUGAN, APPAKALAI N., MIRMIRA, RAGHAVENDRA G., NADLER, JERRY, MASTRACCI, TERESA L., ARVAN, PETER, GREENBAUM, CARLA J., EVANS-MOLINA, CARMELLA
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783367/
https://ncbi.nlm.nih.gov/pubmed/31442418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2019.08.001
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