Abnormalities in proinsulin processing in islets from individuals with longstanding T1D

We recently described the persistence of detectable serum proinsulin in a large majority of individuals with longstanding type 1 diabetes (T1D), including individuals with undetectable serum C-peptide. Here, we sought to further explore the mechanistic etiologies of persistent proinsulin secretion i...

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Vydáno v:Transl Res
Hlavní autoři: SIMS, EMILY K., SYED, FAROOQ, NYALWIDHE, JULIUS, BAHNSON, HENRY T., HAATAJA, LEENA, SPEAKE, CATE, MORRIS, MARGARET A., BALAMURUGAN, APPAKALAI N., MIRMIRA, RAGHAVENDRA G., NADLER, JERRY, MASTRACCI, TERESA L., ARVAN, PETER, GREENBAUM, CARLA J., EVANS-MOLINA, CARMELLA
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783367/
https://ncbi.nlm.nih.gov/pubmed/31442418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2019.08.001
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