Abnormalities in proinsulin processing in islets from individuals with longstanding T1D

We recently described the persistence of detectable serum proinsulin in a large majority of individuals with longstanding type 1 diabetes (T1D), including individuals with undetectable serum C-peptide. Here, we sought to further explore the mechanistic etiologies of persistent proinsulin secretion i...

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Bibliografiska uppgifter
I publikationen:Transl Res
Huvudupphovsmän: SIMS, EMILY K., SYED, FAROOQ, NYALWIDHE, JULIUS, BAHNSON, HENRY T., HAATAJA, LEENA, SPEAKE, CATE, MORRIS, MARGARET A., BALAMURUGAN, APPAKALAI N., MIRMIRA, RAGHAVENDRA G., NADLER, JERRY, MASTRACCI, TERESA L., ARVAN, PETER, GREENBAUM, CARLA J., EVANS-MOLINA, CARMELLA
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783367/
https://ncbi.nlm.nih.gov/pubmed/31442418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2019.08.001
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