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Ras Regulates Sympathetic Neuron Survival by Suppressing the p53-Mediated Cell Death Pathway
In this report, we examine how the Ras protein regulates neuronal survival, focusing on sympathetic neurons. Adenovirus-expressed constitutively activated Ras (RasV12) enhanced survival and the phosphorylation of Akt (protein kinase B) and MAP kinase (MAPK), two targets of Ras activity. Functional i...
Gespeichert in:
| Veröffentlicht in: | J Neurosci |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
1999
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6782948/ https://ncbi.nlm.nih.gov/pubmed/10559381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-22-09716.1999 |
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