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Ras Regulates Sympathetic Neuron Survival by Suppressing the p53-Mediated Cell Death Pathway

In this report, we examine how the Ras protein regulates neuronal survival, focusing on sympathetic neurons. Adenovirus-expressed constitutively activated Ras (RasV12) enhanced survival and the phosphorylation of Akt (protein kinase B) and MAP kinase (MAPK), two targets of Ras activity. Functional i...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Mazzoni, Irene E., Saïd, Farid A., Aloyz, Raquel, Miller, Freda D., Kaplan, David
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782948/
https://ncbi.nlm.nih.gov/pubmed/10559381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-22-09716.1999
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