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Ras Regulates Sympathetic Neuron Survival by Suppressing the p53-Mediated Cell Death Pathway

In this report, we examine how the Ras protein regulates neuronal survival, focusing on sympathetic neurons. Adenovirus-expressed constitutively activated Ras (RasV12) enhanced survival and the phosphorylation of Akt (protein kinase B) and MAP kinase (MAPK), two targets of Ras activity. Functional i...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Mazzoni, Irene E., Saïd, Farid A., Aloyz, Raquel, Miller, Freda D., Kaplan, David
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782948/
https://ncbi.nlm.nih.gov/pubmed/10559381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-22-09716.1999
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