P53 Is Essential for Developmental Neuron Death as Regulated by the TrkA and p75 Neurotrophin Receptors

Naturally occurring sympathetic neuron death is the result of two apoptotic signaling events: one normally suppressed by NGF/TrkA survival signals, and a second activated by the p75 neurotrophin receptor. Here we demonstrate that the p53 tumor suppressor protein, likely as induced by the MEKK-JNK pa...

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Huvudupphovsmän: Aloyz, Raquel S., Bamji, Shernaz X., Pozniak, Christine D., Toma, Jean G., Atwal, Jasvinder, Kaplan, David R., Miller, Freda D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 1998
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132983/
https://ncbi.nlm.nih.gov/pubmed/9852160
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