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Functional interaction between p75(NTR) and TrkA: the endocytic trafficking of p75(NTR) is driven by TrkA and regulates TrkA-mediated signalling

The topology and trafficking of receptors play a key role in their signalling capability. Indeed, receptor function is related to the microenvironment inside the cell, where specific signalling molecules are compartmentalized. The response to NGF (nerve growth factor) is strongly dependent on the tr...

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Détails bibliographiques
Auteurs principaux: Perrone, Lorena, Paladino, Simona, Mazzone, Marialuisa, Nitsch, Lucio, Gulisano, Massimo, Zurzolo, Chiara
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134692/
https://ncbi.nlm.nih.gov/pubmed/15330756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041155
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