Transgenic Mice Expressing the Intracellular Domain of the p75 Neurotrophin Receptor Undergo Neuronal Apoptosis

We have asked whether p75(NTR) may play a role in neuronal apoptosis by producing transgenic mice that express the p75(NTR) intracellular domain within peripheral and central neurons. These animals showed profound reductions in numbers of sympathetic and peripheral sensory neurons as well as cell lo...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Majdan, Marta, Lachance, Christian, Gloster, Andrew, Aloyz, Raquel, Zeindler, Christine, Bamji, Shernaz, Bhakar, Asha, Belliveau, Daniel, Fawcett, James, Miller, Freda D., Barker, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1997
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573268/
https://ncbi.nlm.nih.gov/pubmed/9278534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-18-06988.1997
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