Transgenic Mice Expressing the Intracellular Domain of the p75 Neurotrophin Receptor Undergo Neuronal Apoptosis

We have asked whether p75(NTR) may play a role in neuronal apoptosis by producing transgenic mice that express the p75(NTR) intracellular domain within peripheral and central neurons. These animals showed profound reductions in numbers of sympathetic and peripheral sensory neurons as well as cell lo...

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Publié dans:J Neurosci
Auteurs principaux: Majdan, Marta, Lachance, Christian, Gloster, Andrew, Aloyz, Raquel, Zeindler, Christine, Bamji, Shernaz, Bhakar, Asha, Belliveau, Daniel, Fawcett, James, Miller, Freda D., Barker, Philip A.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1997
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573268/
https://ncbi.nlm.nih.gov/pubmed/9278534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-18-06988.1997
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