Loading...

The Alzheimer's Disease Amyloid Precursor Protein Modulates Copper-Induced Toxicity and Oxidative Stress in Primary Neuronal Cultures

The amyloid precursor protein (APP) of Alzheimer's disease can reduce copper (II) to copper (I) in a cell-free system potentially leading to increased oxidative stress in neurons. We used neuronal cultures derived from APP knock-out (APP(−/−)) and wild-type (WT) mice to examine the role of APP...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: White, Anthony R., Multhaup, Gerd, Maher, Fran, Bellingham, Shayne, Camakaris, James, Zheng, Hui, Bush, Ashley I., Beyreuther, Konrad, Masters, Colin L., Cappai, Roberto
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782934/
https://ncbi.nlm.nih.gov/pubmed/10531420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-21-09170.1999
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!