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Copper Promotes the Trafficking of the Amyloid Precursor Protein

Accumulation of the amyloid β peptide in the cortical and hippocampal regions of the brain is a major pathological feature of Alzheimer disease. Amyloid β peptide is generated from the sequential protease cleavage of the amyloid precursor protein (APP). We reported previously that copper increases t...

詳細記述

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書誌詳細
主要な著者: Acevedo, Karla M., Hung, Ya Hui, Dalziel, Andrew H., Li, Qiao-Xin, Laughton, Katrina, Wikhe, Krutika, Rembach, Alan, Roberts, Blaine, Masters, Colin L., Bush, Ashley I., Camakaris, James
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048711/
https://ncbi.nlm.nih.gov/pubmed/21177866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.128512
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