Caspase-Dependent and -Independent Death of Camptothecin-Treated Embryonic Cortical Neurons

This study investigates the mechanisms underlying death of cultured embryonic cortical neurons exposed to the DNA-damaging agent camptothecin and in particular the interdependence of the roles of cyclin-dependent kinases (Cdks), caspases, and mitochondrial function. Camptothecin evokes rapid neurona...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Stefanis, Leonidas, Park, David S., Friedman, Wilma J., Greene, Lloyd A.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1999
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782831/
https://ncbi.nlm.nih.gov/pubmed/10414953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-15-06235.1999
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