Caspase-2 (Nedd-2) Processing and Death of Trophic Factor-Deprived PC12 Cells and Sympathetic Neurons Occur Independently of Caspase-3 (CPP32)-Like Activity

We have previously shown that caspase-2 (Nedd-2) is required for apoptosis induced by withdrawal of trophic support from PC12 cells and sympathetic neurons. Here, we examine the relationship of caspase-2 processing and cell death to induction of caspase-3 (CPP32)-like activity in PC12 cells. Caspase...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Stefanis, Leonidas, Troy, Carol M., Qi, Haiqing, Shelanski, Michael L., Greene, Lloyd A.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1998
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792876/
https://ncbi.nlm.nih.gov/pubmed/9801360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-22-09204.1998
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