Sendai Virus Infection Induces Apoptosis through Activation of Caspase-8 (FLICE) and Caspase-3 (CPP32)

Sendai virus (SV) infection and replication lead to a strong cytopathic effect with subsequent death of host cells. We now show that SV infection triggers an apoptotic program in target cells. Incubation of infected cells with the peptide inhibitor z-VAD-fmk abrogated SV-induced apoptosis, indicatin...

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Bibliographische Detailangaben
Hauptverfasser: Bitzer, Michael, Prinz, Florian, Bauer, Manuel, Spiegel, Martin, Neubert, Wolfgang J., Gregor, Michael, Schulze-Osthoff, Klaus, Lauer, Ulrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC103877/
https://ncbi.nlm.nih.gov/pubmed/9847376
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