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Sendai Virus Infection Induces Apoptosis through Activation of Caspase-8 (FLICE) and Caspase-3 (CPP32)

Sendai virus (SV) infection and replication lead to a strong cytopathic effect with subsequent death of host cells. We now show that SV infection triggers an apoptotic program in target cells. Incubation of infected cells with the peptide inhibitor z-VAD-fmk abrogated SV-induced apoptosis, indicatin...

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Udgivet i:J Virol
Principais autores: Bitzer, Michael, Prinz, Florian, Bauer, Manuel, Spiegel, Martin, Neubert, Wolfgang J., Gregor, Michael, Schulze-Osthoff, Klaus, Lauer, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103877/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9847376/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.1.702-708.1999
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