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Cyclin-Dependent Kinase Activity Is Required for Apoptotic Death But Not Inclusion Formation in Cortical Neurons after Proteasomal Inhibition

Growing evidence suggests that the proteasome may be dysfunctional in a number of neurodegenerative disorders, including Lewy body diseases. We have reported previously that application of pharmacological inhibitors of the proteasome to cultured cortical neurons leads to apoptotic death and formatio...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Rideout, Hardy J., Wang, Qiaohong, Park, David S., Stefanis, Leonidas
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742273/
https://ncbi.nlm.nih.gov/pubmed/12598612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-04-01237.2003
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