Differential Roles of Nuclear and Cytoplasmic Cyclin-Dependent Kinase 5 in Apoptotic and Excitotoxic Neuronal Death

Cyclin-dependent kinase 5 (cdk5) is a member of the cyclin-dependent kinase family whose activity is localized mainly to postmitotic neurons attributable to the selective expression of its activating partners p35 and p39. Deregulation of cdk5, as a result of calpain cleavage of p35 to a smaller p25...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: O'Hare, Michael J., Kushwaha, Neena, Zhang, Yi, Aleyasin, Hossein, Callaghan, Steven M., Slack, Ruth S., Albert, Paul R., Vincent, Inez, Park, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725602/
https://ncbi.nlm.nih.gov/pubmed/16192386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2899-05.2005
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