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Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models

Huntington disease (HD) is an inherited neurodegenerative disorder characterized by selective death of striatal medium spiny neurons. Intrastriatal injections of glutamate receptor agonists (excitotoxins) recapitulate some neuropathological features of this disorder. Although this model suggests tha...

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Publicat a:J Neurosci
Autors principals: Portera-Cailliau, C, Hedreen, JC, Price, DL, Koliatsos, VE
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578226/
https://ncbi.nlm.nih.gov/pubmed/7751945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-05-03775.1995
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