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Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models

Huntington disease (HD) is an inherited neurodegenerative disorder characterized by selective death of striatal medium spiny neurons. Intrastriatal injections of glutamate receptor agonists (excitotoxins) recapitulate some neuropathological features of this disorder. Although this model suggests tha...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Portera-Cailliau, C, Hedreen, JC, Price, DL, Koliatsos, VE
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578226/
https://ncbi.nlm.nih.gov/pubmed/7751945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.15-05-03775.1995
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