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Mechanisms of Caspase-Independent Neuronal Death: Energy Depletion and Free Radical Generation
Cultured rat embryonic cortical neurons undergo apoptosis when treated with the topoisomerase-I inhibitor camptothecin. Pharmacological or molecular caspase inhibition prevents apoptosis, but the neurons still die in a delayed nonapoptotic manner. Here we examine the mechanisms leading to such caspa...
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| Publicat a: | J Neurosci |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Society for Neuroscience
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6741034/ https://ncbi.nlm.nih.gov/pubmed/14657158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-35-11015.2003 |
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