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Caspase-2 Mediates Neuronal Cell Death Induced by β-Amyloid

β-amyloid (Aβ) has been proposed to play a role in the pathogenesis of Alzheimer's disease (AD). Deposits of insoluble Aβ are found in the brains of patients with AD and are one of the pathological hallmarks of the disease. It has been proposed that Aβ induces death by oxidative stress, possibl...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Troy, Carol M., Rabacchi, Sylvia A., Friedman, Wilma J., Frappier, Thierry F., Brown, Kristy, Shelanski, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772358/
https://ncbi.nlm.nih.gov/pubmed/10662829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-04-01386.2000
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