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A novel and potent brain penetrant inhibitor of extracellular vesicle release
BACKGROUND AND PURPOSE: Extracellular vesicles (EVs) are constitutively shed from cells and released by various stimuli. Their protein and RNA cargo are modified by the stimulus, and in disease conditions can carry pathological cargo involved in disease progression. Neutral sphingomyelinase 2 (nSMas...
Zapisane w:
| Wydane w: | Br J Pharmacol |
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| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
John Wiley and Sons Inc.
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6780992/ https://ncbi.nlm.nih.gov/pubmed/31273753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14789 |
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