A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome

Neuromuscular junction is a synapse between motoneurons and skeletal muscles, where acetylcholine receptors (AChRs) are concentrated to control muscle contraction. Studies of this synapse have contributed to our understanding of synapse assembly and pathological mechanisms of neuromuscular disorders...

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Detalles Bibliográficos
Publicado en:eLife
Autores principales: Xing, Guanglin, Jing, Hongyang, Zhang, Lei, Cao, Yu, Li, Lei, Zhao, Kai, Dong, Zhaoqi, Chen, Wenbing, Wang, Hongsheng, Cao, Rangjuan, Xiong, Wen-Cheng, Mei, Lin
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779466/
https://ncbi.nlm.nih.gov/pubmed/31549961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49180
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