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A valid mouse model of AGRIN-associated congenital myasthenic syndrome

Congenital myasthenic syndromes (CMS) are inherited diseases affecting the neuromuscular junction (NMJ). Mutations in AGRIN (AGRN) and other genes in the AGRIN signaling pathway cause CMS, and gene targeting studies in mice confirm the importance of this pathway for NMJ formation. However, these mou...

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Detalhes bibliográficos
Main Authors: Bogdanik, Laurent P., Burgess, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209832/
https://ncbi.nlm.nih.gov/pubmed/21890498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr396
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