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A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome

Neuromuscular junction is a synapse between motoneurons and skeletal muscles, where acetylcholine receptors (AChRs) are concentrated to control muscle contraction. Studies of this synapse have contributed to our understanding of synapse assembly and pathological mechanisms of neuromuscular disorders...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Xing, Guanglin, Jing, Hongyang, Zhang, Lei, Cao, Yu, Li, Lei, Zhao, Kai, Dong, Zhaoqi, Chen, Wenbing, Wang, Hongsheng, Cao, Rangjuan, Xiong, Wen-Cheng, Mei, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779466/
https://ncbi.nlm.nih.gov/pubmed/31549961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49180
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