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A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome

Neuromuscular junction is a synapse between motoneurons and skeletal muscles, where acetylcholine receptors (AChRs) are concentrated to control muscle contraction. Studies of this synapse have contributed to our understanding of synapse assembly and pathological mechanisms of neuromuscular disorders...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Xing, Guanglin, Jing, Hongyang, Zhang, Lei, Cao, Yu, Li, Lei, Zhao, Kai, Dong, Zhaoqi, Chen, Wenbing, Wang, Hongsheng, Cao, Rangjuan, Xiong, Wen-Cheng, Mei, Lin
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779466/
https://ncbi.nlm.nih.gov/pubmed/31549961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49180
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