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alpha-Actinin interacts with rapsyn in agrin-stimulated AChR clustering

AChR is concentrated at the postjunctional membrane at the neuromuscular junction. However, the underlying mechanism is unclear. We show that α-actinin, a protein known to cross-link F-actin, interacts with rapsyn, a scaffold protein essential for neuromuscular junction formation. α-Actinin, rapsyn,...

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Detalhes bibliográficos
Main Authors: Dobbins, G Clement, Luo, Shiwen, Yang, Zhihua, Xiong, Wen C, Mei, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621155/
https://ncbi.nlm.nih.gov/pubmed/19055765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-1-18
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