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A valid mouse model of AGRIN-associated congenital myasthenic syndrome
Congenital myasthenic syndromes (CMS) are inherited diseases affecting the neuromuscular junction (NMJ). Mutations in AGRIN (AGRN) and other genes in the AGRIN signaling pathway cause CMS, and gene targeting studies in mice confirm the importance of this pathway for NMJ formation. However, these mou...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209832/ https://ncbi.nlm.nih.gov/pubmed/21890498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr396 |
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