The ubiquitination ligase SMURF2 reduces aerobic glycolysis and colorectal cancer cell proliferation by promoting ChREBP ubiquitination and degradation

The glucose-responsive transcription factor carbohydrate response element–binding protein (ChREBP) critically promotes aerobic glycolysis and cell proliferation in colorectal cancer cells. It has been reported that ubiquitination may be important in the regulation of ChREBP protein levels and activi...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Li, Yakui, Yang, Dianqiang, Tian, Na, Zhang, Ping, Zhu, Yemin, Meng, Jian, Feng, Ming, Lu, Ying, Liu, Qi, Tong, Lingfeng, Hu, Lei, Zhang, Lukuan, Yang, James Y., Wu, Lifang, Tong, Xuemei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779433/
https://ncbi.nlm.nih.gov/pubmed/31409643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007508
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