The ubiquitination ligase SMURF2 reduces aerobic glycolysis and colorectal cancer cell proliferation by promoting ChREBP ubiquitination and degradation

The glucose-responsive transcription factor carbohydrate response element–binding protein (ChREBP) critically promotes aerobic glycolysis and cell proliferation in colorectal cancer cells. It has been reported that ubiquitination may be important in the regulation of ChREBP protein levels and activi...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Li, Yakui, Yang, Dianqiang, Tian, Na, Zhang, Ping, Zhu, Yemin, Meng, Jian, Feng, Ming, Lu, Ying, Liu, Qi, Tong, Lingfeng, Hu, Lei, Zhang, Lukuan, Yang, James Y., Wu, Lifang, Tong, Xuemei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779433/
https://ncbi.nlm.nih.gov/pubmed/31409643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007508
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