Identification of HNF-4α as a key transcription factor to promote ChREBP expression in response to glucose

Transcription factor carbohydrate responsive element binding protein (ChREBP) promotes glycolysis and lipogenesis in metabolic tissues and cancer cells. ChREBP-α and ChREBP-β, two isoforms of ChREBP transcribed from different promoters, are both transcriptionally induced by glucose. However, the mec...

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Publicado en:Sci Rep
Main Authors: Meng, Jian, Feng, Ming, Dong, Weibing, Zhu, Yemin, Li, Yakui, Zhang, Ping, Wu, Lifang, Li, Minle, Lu, Ying, Chen, Hanbei, Liu, Xing, Lu, Yan, Sun, Haipeng, Tong, Xuemei
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814918/
https://ncbi.nlm.nih.gov/pubmed/27029511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23944
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