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Identification of HNF-4α as a key transcription factor to promote ChREBP expression in response to glucose
Transcription factor carbohydrate responsive element binding protein (ChREBP) promotes glycolysis and lipogenesis in metabolic tissues and cancer cells. ChREBP-α and ChREBP-β, two isoforms of ChREBP transcribed from different promoters, are both transcriptionally induced by glucose. However, the mec...
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| Vydáno v: | Sci Rep |
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| Hlavní autoři: | , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814918/ https://ncbi.nlm.nih.gov/pubmed/27029511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23944 |
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