Integrated Expression Profiling and Genome-Wide Analysis of ChREBP Targets Reveals the Dual Role for ChREBP in Glucose-Regulated Gene Expression

The carbohydrate response element binding protein (ChREBP), a basic helix-loop-helix/leucine zipper transcription factor, plays a critical role in the control of lipogenesis in the liver. To identify the direct targets of ChREBP on a genome-wide scale and provide more insight into the mechanism by w...

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Main Authors: Jeong, Yun-Seung, Kim, Deokhoon, Lee, Yong Seok, Kim, Ha-Jung, Han, Jung-Youn, Im, Seung-Soon, Chong, Hansook Kim, Kwon, Je-Keun, Cho, Yun-Ho, Kim, Woo Kyung, Osborne, Timothy F., Horton, Jay D., Jun, Hee-Sook, Ahn, Yong-Ho, Ahn, Sung-Min, Cha, Ji-Young
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141076/
https://ncbi.nlm.nih.gov/pubmed/21811631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022544
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