The ubiquitination ligase SMURF2 reduces aerobic glycolysis and colorectal cancer cell proliferation by promoting ChREBP ubiquitination and degradation

The glucose-responsive transcription factor carbohydrate response element–binding protein (ChREBP) critically promotes aerobic glycolysis and cell proliferation in colorectal cancer cells. It has been reported that ubiquitination may be important in the regulation of ChREBP protein levels and activi...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Li, Yakui, Yang, Dianqiang, Tian, Na, Zhang, Ping, Zhu, Yemin, Meng, Jian, Feng, Ming, Lu, Ying, Liu, Qi, Tong, Lingfeng, Hu, Lei, Zhang, Lukuan, Yang, James Y., Wu, Lifang, Tong, Xuemei
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2019
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779433/
https://ncbi.nlm.nih.gov/pubmed/31409643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007508
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