The ubiquitination ligase SMURF2 reduces aerobic glycolysis and colorectal cancer cell proliferation by promoting ChREBP ubiquitination and degradation

The glucose-responsive transcription factor carbohydrate response element–binding protein (ChREBP) critically promotes aerobic glycolysis and cell proliferation in colorectal cancer cells. It has been reported that ubiquitination may be important in the regulation of ChREBP protein levels and activi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Li, Yakui, Yang, Dianqiang, Tian, Na, Zhang, Ping, Zhu, Yemin, Meng, Jian, Feng, Ming, Lu, Ying, Liu, Qi, Tong, Lingfeng, Hu, Lei, Zhang, Lukuan, Yang, James Y., Wu, Lifang, Tong, Xuemei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779433/
https://ncbi.nlm.nih.gov/pubmed/31409643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007508
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