The ubiquitination ligase SMURF2 reduces aerobic glycolysis and colorectal cancer cell proliferation by promoting ChREBP ubiquitination and degradation

The glucose-responsive transcription factor carbohydrate response element–binding protein (ChREBP) critically promotes aerobic glycolysis and cell proliferation in colorectal cancer cells. It has been reported that ubiquitination may be important in the regulation of ChREBP protein levels and activi...

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Vydáno v:J Biol Chem
Hlavní autoři: Li, Yakui, Yang, Dianqiang, Tian, Na, Zhang, Ping, Zhu, Yemin, Meng, Jian, Feng, Ming, Lu, Ying, Liu, Qi, Tong, Lingfeng, Hu, Lei, Zhang, Lukuan, Yang, James Y., Wu, Lifang, Tong, Xuemei
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779433/
https://ncbi.nlm.nih.gov/pubmed/31409643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007508
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