Structural basis of Type IV CRISPR RNA biogenesis by a Cas6 endoribonuclease

Prokaryotic CRISPR-Cas adaptive immune systems rely on small non-coding RNAs derived from CRISPR loci to recognize and destroy complementary nucleic acids. However, the mechanism of Type IV CRISPR RNA (crRNA) biogenesis is poorly understood. To dissect the mechanism of Type IV CRISPR RNA biogenesis,...

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Dades bibliogràfiques
Publicat a:RNA Biol
Autors principals: Taylor, Hannah N., Warner, Emily E., Armbrust, Matthew J., Crowley, Valerie M., Olsen, Keith J., Jackson, Ryan N.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779396/
https://ncbi.nlm.nih.gov/pubmed/31232162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1634965
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